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Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

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It was first suggested that importation of StAR into mitochondria formed contact points between the OMM and IMM, permitting cholesterol to flow down a chemical concentration gradient (136, 199), and others concluded that the 30 kDa mature StAR is the biologically active moiety, functioning as a cholesterol shuttle in the intramembranous space (207)